MK-677, also known as Ibutamoren, is an oral growth hormone secretagogue. Instead of being a peptide injection, MK-677 is taken as a pill, making it extremely popular among beginners and fitness users. It is commonly discussed for improving sleep quality, enhancing recovery, stimulating appetite, and increasing natural GH and IGF-1 levels.
Commonly Reported Benefits
- Deeper, more restorative sleep
- Increased appetite (helpful for bulking phases)
- Improved recovery and reduced soreness
- Potential increases in lean muscle gain
- Higher GH and IGF-1 levels compared to many peptides
How MK-677 Works
MK-677 mimics ghrelin, a hunger hormone, and stimulates the brain to release more natural growth hormone. Unlike peptides such as CJC-1295 or Ipamorelin, MK-677 works via the oral pathway and has a very long half-life — often 24 hours or more.
How It’s Typically Used
Most users take MK-677 once daily, typically before bed or in the evening due to the effect on sleep and appetite. Because it can increase water retention early on, protocols often start low and increase slowly under medical supervision.
Safety Notes
Common side effects include increased appetite, vivid dreams, water retention, and insulin sensitivity changes with long-term use. It should only be used under the guidance of a qualified healthcare provider who understands your medical background.